Codes and Coverage

Supporting patient access

BMS Access Support® may help support patient access by conducting benefits reviews and offering prior authorization and appeals process assistance for enrolled patients. Additionally, the information below provides product-specific billing and diagnosis codes, reimbursement and coding guides, distribution information, and additional coverage support offerings. To view available coding and coverage information, please select your patient’s prescribed medication.

Additional eligibility criteria and terms may apply. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.

OPDIVO QVANTIG

(nivolumab and hyaluronidase-nvhy)

The accurate completion of reimbursement- or coverage-related documentation is the responsibility of the healthcare provider and patient. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.

Explore codes on this page:      ⬇HCPCS      ⬇Revenue Codes      ⬇CPT      ⬇NDC      ⬇ICD-10

Providers and suppliers are required to report the JW modifier on Part B drug claims for unused drugs and biologicals that are appropriately discarded. Also, providers and suppliers must document the amount of discarded drugs or biologicals in Medicare beneficiaries’ medical records.1

Providers and suppliers are required to report the JZ modifier to attest if there were no discarded amounts of drugs and biologicals.1

Healthcare Common Procedure Coding System (HCPCS) Codes2

Issued by CMS

J9289 Injection, nivolumab, 2 mg and hyaluronidase-nvhy
Revenue Codes (for Hospital Use)3
0636 Drugs requiring detailed coding
0250 Pharmacy (General)
0331 Chemotherapy administration, injected
Current Procedural Terminology (CPT)4
96401 Chemotherapy administration, SC or intramuscular; non-hormonal anti-neoplastic
National Drug Codes (NDC)5

Issued by the FDA
Note: Payers require the submission of the 11-digit NDC on healthcare claim forms. Please use the 11-digit codes shown here.

00003-3120-01 300 mg nivolumab and 5,000 units hyaluronidase per 2.5 mL (120 mg/2,000 units per mL) single dose vial
00003-6120-01 600 mg nivolumab and 10,000 units hyaluronidase per 5 mL (120 mg/2,000 units per mL) single dose vial
International Classification of Diseases, Tenth Revision, Clinical Modification Diagnosis Codes (ICD-10-CM)6

Coding for OPDIVO QVANTIG is dependent on the insurer and the care setting in which the drug will be administered. Oncology practices need to make coding decisions based on the diagnosis and treatment of each patient and the specific insurer requirements.

Please see U.S. Full Prescribing Information for OPDIVO QVANTIG.

*Healthcare providers should code healthcare claims based upon the service that is rendered, the patient's medical record, the coding requirements of each health insurer, and best coding practices. Coding information provided under this heading does not provide a guarantee of reimbursement and should be considered together with all applicable coding guidance and standards. All of the coding information presented by this website is applicable to outpatient procedures only.

CPT codes and descriptions only are ©2025 by American Medical Association (AMA). All rights reserved. The AMA assumes no liability for data contained or not contained herein. CPT is a registered trademark of the American Medical Association.

This is a category code and is invalid for stand-alone use. Please select one of the expanded codes listed below.

References:

  1. Centers for Medicare & Medicaid Services. Discarded Drugs and Biologicals – JW Modifier and JZ Modifier Policy. https://www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/HospitalOutpatientPPS/Downloads/JW-Modifier-FAQs.pdf. Accessed January 27, 2026.
  2. American Medical Association. HCPCS Level II Expert 2025. American Medical Association; 2024.
  3. National Uniform Billing Committee (NUBC). Official UB-04 Data Specifications Manual 2020. Chicago, IL: American Hospital Association; 2020.
  4. American Medical Association. CPT 2025 Professional Edition. American Medical Association; 2024.
  5. OPDIVO QVANTIG [package insert]. Princeton, NJ: Bristol-Myers Squibb Company.
  6. Centers for Medicare & Medicaid Services. 2026 ICD-10-CM tabular list of diseases and injuries. https://www.cms.gov/files/zip/2026-code-tables-tabular-and-index.zip. Accessed January 27, 2026.

OPDIVO QVANTIG may be purchased through the distributors listed below.

 

Physician Offices

For offices that prefer to use the services of a specialty pharmacy, specialty pharmacies can obtain OPDIVO QVANTIG from the distributors listed above.

Hospitals and Infusion Centers

Puerto Rico Hospitals and Clinics

Above information is accurate as of 01/26.

The OPDIVO QVANTIG distribution program includes extended payment terms to Bristol Myers Squibb authorized OPDIVO QVANTIG distributors. Healthcare providers and institutions should contact their OPDIVO QVANTIG distributor to understand specific payment terms that may be available to them from their distributor.

Please see U.S. Full Prescribing Information for OPDIVO QVANTIG.

FDA Approval Letters as Posted by the FDA:

Claim Forms for Outpatient Administration

Sample CMS-1500
Physician Office

Sample UB-04/CMS-1450
Hospital Outpatient

See Payer Policy Details

Learn about payer information by state for applicable treatments.